abstract：INTRODUCTION:The objective of this study was to determine whether the effect of isoproterenol (Iso) to increase L-type Ca2+ current [I(Ca(L))] and action potential duration (APD) was potentiated in ventricular myocytes following termination of an exposure of these cells to acetylcholine (ACh), and whether this potentia...

journal_title：Journal of cardiovascular electrophysiology

authors： Song Y,Shryock JC,Belardinelli L

更新日期：1998-07-01 00:00:00

abstract：INTRODUCTION:Following radiofrequency catheter ablation of AV nodal reentrant tachycardia (AVNRT), inappropriate sinus tachycardia may occur, possibly due to damage to autonomic cardiac nerve fibers. Furthermore, inducibility of AVNRT is often critically dependent on the autonomic balance. We investigated whether succe...

journal_title：Journal of cardiovascular electrophysiology

authors： Kowallik P,Escher S,Peters W,Braun C,Meesmann M

更新日期：1998-06-01 00:00:00

abstract：INTRODUCTION:The application of high-frequency current to the AV junctional area results in a temperature rise in the myocardium and may cause accelerated junctional rhythm (AJR). The aim of the study was to characterize heat-induced AJR in an in vitro animal model. METHODS AND RESULTS:Studies were performed in isolat...

journal_title：Journal of cardiovascular electrophysiology

authors： Thibault B,de Bakker JM,Hocini M,Loh P,Wittkampf FH,Janse MJ

更新日期：1998-06-01 00:00:00

abstract：INTRODUCTION:The upper limit of vulnerability (ULV) correlates with the defibrillation threshold (DFT). The ULV can be determined with a single episode of ventricular fibrillation and is more reproducible than the single-point DFT. The critical-point hypothesis of defibrillation predicts that the relation between the U...

journal_title：Journal of cardiovascular electrophysiology

authors： Swerdlow CD,Kass RM,O'Connor ME,Chen PS

更新日期：1998-04-01 00:00:00

abstract：INTRODUCTION:Syncope occasionally may occur in the supine patient due to severe brady- or tachyarrhythmia. However, recurrent syncope upon assumption of the supine position as a result of a neurally mediated reflex mechanism has not been reported previously. METHODS AND RESULTS:Two young patients, both of whom had sig...

journal_title：Journal of cardiovascular electrophysiology

authors： Iskos D,Shultz JJ,Benditt DG

更新日期：1998-04-01 00:00:00

abstract：INTRODUCTION:The advent of signal-averaged ECG (SAECG) systems for P wave analysis has made it important to determine if the use of different filtering techniques in these systems is diagnostically equivalent. METHODS AND RESULTS:Three different high-pass filtering techniques and two cutoff frequency values were used:...

journal_title：Journal of cardiovascular electrophysiology

authors： Valverde ER,Quinteiro RA,Bertran GC,Arini PD,Glenny P,Biagetti MO

更新日期：1998-03-01 00:00:00

abstract：INTRODUCTION:Regional dispersions of repolarization (DOR) are arrhythmogenic perturbations that are closely associated with reentry. However, the characteristics of DOR have not been well defined or adequately analyzed because previous algorithms did not take into account spatial heterogeneities of action potential dur...

journal_title：Journal of cardiovascular electrophysiology

authors： Salama G,Kanai AJ,Huang D,Efimov IR,Girouard SD,Rosenbaum DS

更新日期：1998-02-01 00:00:00

abstract：INTRODUCTION:The role of increased dispersion of repolarization in the genesis of torsades de pointes in patients with long QT syndrome has been clarified, but its role in the genesis of idiopathic ventricular fibrillation (VF) is not yet known. To investigate the pathogenesis of VF, we recorded monophasic action poten...

journal_title：Journal of cardiovascular electrophysiology

authors： Matsuo K,Shimizu W,Kurita T,Suyama K,Aihara N,Kamakura S,Shimomura K

更新日期：1998-01-01 00:00:00

abstract：INTRODUCTION:The difficult catheter orientation and navigation associated with conventional technology and mono-/multiplane fluoroscopy may complicate ablation procedures of atrial tachycardias. A new three-dimensional catheter technology for electroanatomical mapping of the right atrium and ablation of ectopic atrial ...

journal_title：Journal of cardiovascular electrophysiology

authors： Kottkamp H,Hindricks G,Breithardt G,Borggrefe M

更新日期：1997-12-01 00:00:00

abstract：INTRODUCTION:Blockade of the rapid delayed rectifier potassium current (IKr) as an important mechanism for current Class III antiarrhythmics is less effective in action potential prolongation during beta-adrenergic activation. We hypothesized that blockade of the increased slow IK (IKs) current during beta-adrenergic s...

journal_title：Journal of cardiovascular electrophysiology

authors： Schreieck J,Wang Y,Gjini V,Korth M,Zrenner B,Schömig A,Schmitt C

更新日期：1997-12-01 00:00:00

abstract：INTRODUCTION:Amiodarone is a potent antiarrhythmic agent used in the management of both atrial and ventricular arrhythmias. In addition to its beta-blocking properties, amiodarone is known to block the sodium, potassium, and calcium channels in the heart. Its complex electropharmacology notwithstanding, the reasons for...

journal_title：Journal of cardiovascular electrophysiology

authors： Sicouri S,Moro S,Litovsky S,Elizari MV,Antzelevitch C

更新日期：1997-11-01 00:00:00

abstract：INTRODUCTION:Ventricular tachycardia (VT) after postinfarct ventricular septal defect (VSD) repair has not been well characterized. METHODS AND RESULTS:A 55-year-old man developed refractory VT after inferior wall infarction and VSD repair. Entrainment demonstrated a broad reentry circuit path (outer loop) between the...

journal_title：Journal of cardiovascular electrophysiology

authors： Ellison KE,Stevenson WG,Couper GS,Friedman PL

更新日期：1997-10-01 00:00:00

abstract：INTRODUCTION:The aims of this study were to investigate: (1) the effect of supplementing the culture medium on preservation of L-type calcium channel current (1Ca,L) in adult rabbit ventricular myocytes cultured for 4 days; and (2) preservation of the ICa,L response in cultured myocytes to the beta-adrenergic agonist i...

journal_title：Journal of cardiovascular electrophysiology

authors： Mitcheson JS,Hancox JC,Levi AJ

更新日期：1997-09-01 00:00:00

abstract：INTRODUCTION:Isoproterenol is used to assess and facilitate AV nodal conduction, and thus potentiate the induction of supraventricular arrhythmias. It is commonly administered in increasing doses until a predetermined decrease in sinus cycle length, usually 20% to 30%, occurs. This regimen may result in undesirable sid...

journal_title：Journal of cardiovascular electrophysiology

authors： Cossú SF,Rothman SA,Chmielewski IL,Hsia HH,Vogel RL,Miller JM,Buxton AE

更新日期：1997-08-01 00:00:00

abstract：:Atrial fibrillation is the most common sustained tachyarrhythmia and, as such, has become the recent focus of intense clinical and experimental interest. Because of its associated morbidity and mortality, there is a multidisciplinary effort to understand the pathophysiology that may ultimately lead to improved therape...

journal_title：Journal of cardiovascular electrophysiology

authors： Zipes DP

更新日期：1997-08-01 00:00:00

abstract：INTRODUCTION:A functional region of slow conduction located in the inferior right atrium has been postulated to be critical to the induction and maintenance of typical human atrial flutter. We reexamined the potential role of functional conduction delay in the annular isthmus between the tricuspid valve and the inferio...

journal_title：Journal of cardiovascular electrophysiology

authors： Kinder C,Kall J,Kopp D,Rubenstein D,Burke M,Wilber D

更新日期：1997-07-01 00:00:00

abstract：:In an era when many electrophysiologic problems are routinely treated with invasive procedures or implantable devices, drugs remain the cornerstones of treatment for atrial fibrillation. Atrial fibrillation may present as an episodic rhythm in patients who are primarily in sinus rhythm or it may be manifested as rhyth...

journal_title：Journal of cardiovascular electrophysiology

authors： Riley RD,Pritchett EL

更新日期：1997-07-01 00:00:00

abstract：INTRODUCTION:Bundle branch reentry ventricular tachycardia (VT) is usually amenable to treatment with radiofrequency ablation. Different QRS morphologies during VT are possible when anterograde ventricular activation is over the left bundle branch. Manifestations of this reentrant tachycardia with more than one QRS mor...

journal_title：Journal of cardiovascular electrophysiology

authors： Wang CW,Sterba R,Tchou P

更新日期：1997-06-01 00:00:00

abstract：INTRODUCTION:Determination of the optimal electrode configuration during implantable cardioverter defibrillator (ICD) implantation remains largely an empirical process. This study investigated the feasibility of using a finite element model of the thorax to predict clinical defibrillation metrics for internal defibrill...

journal_title：Journal of cardiovascular electrophysiology

authors： Kinst TF,Sweeney MO,Lehr JL,Eisenberg SR

更新日期：1997-05-01 00:00:00

abstract：INTRODUCTION:Idiopathic left ventricular tachycardia typically has a right bundle branch block configuration. The purpose of this case report is to demonstrate that idiopathic ventricular tachycardia arising in or near the left posterior fascicle also may have a left bundle branch block configuration. METHODS AND RESU...

journal_title：Journal of cardiovascular electrophysiology

authors： Zivin A,Goyal R,Daoud E,Man KC,Strickberger SA,Morady F

更新日期：1997-04-01 00:00:00

abstract：INTRODUCTION:Ventricular arrhythmias are a common feature in patients with mitral valve prolapse. In an attempt to determine the origin and underlying electrophysiologic mechanism, we describe a patient with ventricular fibrillation, exercise-induced ventricular tachycardia (VT), and, at the time of diagnosis, prolapse...

journal_title：Journal of cardiovascular electrophysiology

authors： Wilde AA,Düren DR,Hauer RN,deBakker JM,Bakker PF,Becker AE,Janse MJ

更新日期：1997-03-01 00:00:00

abstract：INTRODUCTION:How cell-to-cell electrical coupling influences an antiarrhythmic agent's effect on conduction is largely unknown. To investigate this, we evaluated the effects of procainamide on myocardial conduction at decreasing degrees of cell-to-cell electrical coupling induced by graded doses of heptanol. METHODS A...

journal_title：Journal of cardiovascular electrophysiology

authors： Spear JF,Hook BG,Josephson ME,Moore EN

更新日期：1997-02-01 00:00:00

abstract：INTRODUCTION:Despite innovations in nonthoracotomy defibrillation systems, thoracotomies are still required in some clinical settings and are utilized in many animal-based research protocols. The effect of a thoracotomy on defibrillation energy, however, has not been well characterized. METHODS AND RESULTS:Ten dogs in...

journal_title：Journal of cardiovascular electrophysiology

authors： Friedman PA,Stanton MS

更新日期：1997-01-01 00:00:00

abstract：INTRODUCTION:Idiopathic ventricular tachycardia (VT) originating in or close to the anterior fascicle of the left bundle is rare. A patient with no structural heart disease and VT with a right bundle branch block configuration and right-axis deviation underwent an electrophysiologic examination. METHODS AND RESULTS:Bo...

journal_title：Journal of cardiovascular electrophysiology

authors： Rodriguez LM,Smeets JL,Timmermans C,Trappe HJ,Wellens HJ

更新日期：1996-12-01 00:00:00

abstract：:We describe a patient with bundle branch reentry ventricular tachycardia with 1:1 VA conduction in whom resetting was performed while obtaining simultaneous recordings from the right ventricular apex (V) and His-bundle electrogram. Both the tachycardia return cycle and the V-His interval demonstrated an increasing res...

journal_title：Journal of cardiovascular electrophysiology

authors： Sarter BH,Schwartzman D,Callans DJ,Gottlieb CD,Marchlinski FE

更新日期：1996-11-01 00:00:00

abstract：:The signal-averaged electrocardiogram (SAECG) facilitates noninvasive recording of low-amplitude cardiac signals such as ventricular late potentials. The SAECG has been used to accurately predict life-threatening ventricular tachyarrhythmias in patients after acute myocardial infarction and with nonischemic dilated ca...

journal_title：Journal of cardiovascular electrophysiology

authors： Steinberg JS,Berbari EJ

更新日期：1996-10-01 00:00:00

abstract：INTRODUCTION:Previous studies suggest that class III antiarrhythmic drugs are more effective in reentrant arrhythmias because they prolong refractoriness (ERP) and wavelength and reduce dispersion of refractoriness compared to Class IA antiarrhythmic drugs, which slow conduction velocity (CV) in addition to their effec...

journal_title：Journal of cardiovascular electrophysiology

authors： Cha Y,Wales A,Wolf P,Shahrokni S,Sawhney N,Feld GK

更新日期：1996-09-01 00:00:00

abstract：INTRODUCTION:The stability of implantable cardiac defibrillation lead impedance subsequent to implantation has not been reported and may have important clinical implications. The objective was to characterize the incidence and degree of impedance changes occurring after implantation of defibrillation lead systems. MET...

journal_title：Journal of cardiovascular electrophysiology

authors： Schwartzman D,Hull ML,Callans DJ,Gottlieb CD,Marchlinski FE

更新日期：1996-08-01 00:00:00

abstract：:The promise of atomic (scanning) force microscopy (AFM) for cardiovascular research is enormous. The AFM images by using a sharp cantilever tip to sense the repulsive and attractive forces between the tip and the sample surface. The force of interaction is kept constant while raster scanning, resulting in images of th...

journal_title：Journal of cardiovascular electrophysiology

authors： Arnsdorf MF,Xu S

更新日期：1996-07-01 00:00:00

abstract：:We report a case of pericardial constriction associated with defibrillator patches developing 4.5 years after implantation. This constriction was related to the presence of a large pericardial mass that had developed above the defibrillator patch. This mass, which had a calcified superior border, suggested former hema...

journal_title：Journal of cardiovascular electrophysiology

authors： Le Tourneau T,Klug D,Lacroix D,Kacet S,Lekieffre J

更新日期：1996-06-01 00:00:00

abstract：:Autonomic dysfunction may occur as a consequence of radiofrequency (RF) catheter ablation of a variety of supraventricular tachycardias. Effects suggestive of autonomic dysfunction that may be seen acutely during the ablation procedure include sudden profound slowing of the sinus rate or transient AV block. These abno...

journal_title：Journal of cardiovascular electrophysiology

authors： Friedman PL,Stevenson WG,Kocovic DZ

更新日期：1996-05-01 00:00:00

abstract：INTRODUCTION:The reason for the increased defibrillation efficacy of biphasic shocks over monophasic shock is not definitely known. METHODS AND RESULTS:In six anesthetized pigs, we mapped the epicardium after transvenous defibrillation shocks to compare the activation patterns following successful biphasic shocks with...

journal_title：Journal of cardiovascular electrophysiology

authors： Usui M,Callihan RL,Walker RG,Walcott GP,Rollins DL,Wolf PD,Smith WM,Ideker RE

更新日期：1996-04-01 00:00:00

abstract：:A case of intermittent sinus parasystole in which the parasystolic focus is protected from the dominant sinus rhythm only during the second half of its intrinsic cycle is reported. In addition, a modulating (i.e., electronic) effect is often clearly exerted from the dominant rhythm upon the focus during the protected ...

journal_title：Journal of cardiovascular electrophysiology

authors： Satullo G,Donato A,Busá G,Cavallaro L

更新日期：1996-03-01 00:00:00

abstract：INTRODUCTION:Frequency-dependent electrophysiologic actions of oral quinidine and oral sotalol may be clinically important, but these properties and their modulation by beta-adrenergic sympathetic stimulation have not been determined. METHODS AND RESULTS:The frequency-dependent effects of oral quinidine (n = 17) and o...

journal_title：Journal of cardiovascular electrophysiology

authors： Sager PT,Behboodikhah M

更新日期：1996-02-01 00:00:00

abstract：INTRODUCTION:Capacitance is known to influence defibrillation. Optimal biphasic waveform capacitance for transvenous unipolar defibrillation systems in man is currently being defined. In an effort to improve defibrillation efficacy, we examined the relative defibrillation efficacy of a 65% tilt biphasic pulse from a 90...

journal_title：Journal of cardiovascular electrophysiology

authors： Poole JE,Kudenchuk PJ,Dolack GL,Jones GK,Degroot P,Johnson G,Bardy GH

更新日期：1995-12-01 00:00:00

abstract：INTRODUCTION:As treatment options for ventricular tachycardia (VT) continue to evolve, the use of radiofrequency catheter ablation is rapidly expanding. However, in the presence of multiple morphologies of VT, achieving successful results may seem less likely. We report two patients with multiple morphologies of VT who...

journal_title：Journal of cardiovascular electrophysiology

authors： Underwood RD,Deshpande SS,Biehl M,Cowan M,Akhtar M,Jazayeri MR

更新日期：1995-11-01 00:00:00

abstract：:Application of radiofrequency energy to arrhythmogenic substrates after careful cardiac mapping could ensure a high success rate in eliminating certain types of tachyarrhythmias. Future studies of catheter ablation will focus on how to improve ablation efficacy and achieve a better result in various types of tachyarrh...

journal_title：Journal of cardiovascular electrophysiology

authors： Chen SA,Chiang CE,Tai CT,Lee SH,Chang MS

更新日期：1995-10-01 00:00:00

abstract：:The evidence that antiarrhythmic compounds that act by slowing conduction velocity increase mortality in patients with cardiac disease is now compelling. Emphasis is now shifting to agents that act by lengthening repolarization and have additional antiadrenergic properties. There is preliminary evidence that pure Clas...

journal_title：Journal of cardiovascular electrophysiology

authors： Singh BN

更新日期：1995-10-01 00:00:00

abstract：INTRODUCTION:The purpose of this study is to describe a simple and reliable diagnostic maneuver that allows for the rapid differentiation of atypical AV nodal reentrant tachycardia (AVNRT) from other causes of long RP tachycardia. Long RP tachycardias may be caused by atypical AVNRT, orthodromic reciprocating tachycard...

journal_title：Journal of cardiovascular electrophysiology

authors： Man KC,Niebauer M,Daoud E,Strickberger SA,Kou W,Williamson BD,Morady F

更新日期：1995-09-01 00:00:00

abstract：INTRODUCTION:Radiofrequency (RF) ablation of ventricular tachycardia (VT) late after myocardial infarction may be difficult due to characteristics of the infarct containing the reentry circuit. RF lesions in these infarcts in humans have not been characterized. METHODS AND RESULTS:Catheter mapping and ablation of VT o...

journal_title：Journal of cardiovascular electrophysiology

authors： Bartlett TG,Mitchell R,Friedman PL,Stevenson WG

更新日期：1995-08-01 00:00:00